BIOCHEMISTRY

Q: Which of the following is true regarding Okazaki fragment?

(a) :  Are segments of RNA attached to an RNA initiator component
(b) :  Are related to the leading strand
(c) :  Several Okazaki fragments must be sequentially synthesized for each replication fork
(d) :  Helicase acts on the leading strand to unwind dsDNA
(e) :  None of the above
Answer:  Several Okazaki fragments must be sequentially synthesized for each replication fork
Explanation:  

Q: The enzyme catalyzing the production of orotidylic acid is?

(a) :  Dihydro orotase
(b) :  Aspartyl transcarbamoylase
(c) :  Dihydro orotate dehydrogenase
(d) :  Orotate phosphoribosyl transferase
(e) :  None of the above
Answer:  Orotate phosphoribosyl transferase
Explanation:  

Q: All are disorders due to peroxisomal abnormalities except?

(a) :  Pfeiffer syndrome
(b) :  Zellweger syndrome
(c) :  Hyperoxaluria type 1
(d) :  Acatalasemia
(e) :  None of the above
Answer:  Pfeiffer syndrome
Explanation:  

Q: Deficiency of lysyl hydroxylase causes?

(a) :  Alport syndrome
(b) :  Menkes disease
(c) :  Epidermolysis bullosa
(d) :  Osteogenesis imperfecta
(e) :  None of the above
Answer:  Menkes disease
Explanation:  

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