Pharmacology

Q: Most antipsychotic drugs can be said to have which of the following actions?

(a) :  cholinergic
(b) :  dopaminergic
(c) :  COMT inhibition
(d) :  dopamine inhibition
(e) :  alpha1-adrenergic agonist
Answer:  dopamine inhibition
Explanation:   Most antipsychotic agents are believed to act by antagonizing dopamine receptors. They may also cause some blockade of cholinergic, alphaI-adrenergic, and histamine receptors.

Q: Which of the following agents is (are) classi-fied as antiseptics or germicides? I. chlorhexidine gluconate (Hibiclens) II. glutaraldehyde (Cidex) III. benzalkonium chloride (Zephiran)

(a) :  I only
(b) :  III only
(c) :  I and II only
(d) :  II and III only
(e) :  I, II, and III
Answer:  I, II, and III
Explanation:   Chlorhexidine gluconate (Hibiclens, Betasept), glutaraldehyde (Cidex), and benzal-konium chloride (Zephiran) are antiseptic agents used either as surgical scrubs or for the disinfection of surgical and dental equipment.

Q: Morphine can be expected to produce which of the following pharmacological effects? I. dilation of the pupils II. respiratory depression III. constipation

(a) :  I only
(b) :  III only
(c) :  I and II only
(d) :  II and III only
(e) :  I, II, and III
Answer:  II and III only
Explanation:  Constipation is a common effect because morphine decreases peristaltic activity in the GI tract. Constriction of the pupils, CNS and respiratory depression, and nausea and vomiting are all effects also associated with morphine use.

Q: Selegeline (Eldepryl) can best be described as a (an)

(a) :  MAO inhibitor
(b) :  anticholinergi
(c) :  COMT inhibitor
(d) :  anticonvulsant
(e) :  alpha! agonist
Answer:  MAO inhibitor
Explanation:   Selegeline (Eldepryl) is an MAO-B inhibitor that is used in the adjunctive treatment of Parkinson's disease.

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